SUMMARY
Windows Vista and Windows 2008 Server both use a different security model compared to previous versions of Windows. One of the new features prevents even Administrator credentials from writing to the registry automatically. To correctly install or register ASNA products on Vista or Win2008 Server you must right click the installation package or Registration Assistant and choose "Run as Administrator"
DETAILS
The information below is an excerpt from the following Microsoft article.
http://technet.microsoft.com/en-us/library/cc709691.aspx
When an administrator logs on to a computer running Windows Vista, the user is assigned two separate access tokens. Access tokens, which contain a user's group membership and authorization and access control data, are used by Windows® to control what resources and tasks the user can access. Before Windows Vista, an administrator account received only one access token, which included data to grant the user access to all Windows resources.
To help prevent malicious software from silently installing and causing computer-wide infection, Microsoft developed the UAC feature. Unlike previous versions of Windows, when an administrator logs on to a computer running Windows Vista, the user’s full administrator access token is split into two access tokens: a full administrator access token and a standard user access token. During the logon process, authorization and access control components that identify an administrator are removed, resulting in a standard user access token. The standard user access token is then used to start the desktop, the Explorer.exe process. Because all applications inherit their access control data from the initial launch of the desktop, they all run as a standard user as well.
SYMPTOMS
When installing ASNA products without right clicking and choosing "Run as Administrator" you may recieve "File not Found" or "Cannot create Folder" errors.
When registering ASNA products without right clicking and choosing "Run as Administrator" the registration assistant appears to complete successfully but you still recieve "License Expired" or "User count exceeded" errors.
CAUSE
The User Account Control (UAC)
RESOLUTION
Right click and choose "Run as Administrator"

MORE INFORMATION
http://technet.microsoft.com/en-us/library/cc709691.aspx